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Glen Pyle

Glen Pyle

Professor, University of Guelph
I am a Principal Investigator of a lab that investigates heart failure. Our group focuses on the molecular basis of heart failure, and the impact of elements like sex and ageing on heart failure. In collaboration with our colleagues in veterinary cardiology we have conducted research into a naturally occurring form of heart failure called 'dilated cardiomyopathy' (DCM). Almost half of all Doberman Pinschers die from DCM. The similarities between canine heart failure and human heart failure allows us to apply our research in both human and veterinary medicine. Our research into the fundamental science behind heart failure has lead to novel lines of investigation including biomarkers for the identification of heart failure in its early stages, and new molecular therapies for failing hearts.

Menopause? Start estrogen replacement therapy sooner, to reduce heart disease

Jun 07, 2019 16:09 pm UTC| Insights & Views Health

Hormone replacement therapy for post-menopausal women was once seen as a fountain of youth. Studies showed regular estrogen supplementation decreased the risk of cardiovascular disease, the leading cause of death in...

Get the flu shot – to lower your risk of a heart attack

Nov 04, 2018 14:27 pm UTC| Insights & Views Health

Were the members of the legendary musical group Bon Jovi medical visionaries? How else do you explain Shot to the Heart? This prophetic song predicted the protective benefits of the flu shot against heart disease more than...

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Economy

German bunds rally after Q4 GDP disappoints investors; ECB’s Lagarde in focus

The German bunds rallied during afternoon session of second first trading day of the week Tuesday after the countrys gross domestic product (GDP) for the fourth quarter of 2019, released today, disappointed market...

CNY unlikely to recover solidly given overnight risk-off sentiment, says Commerzbank

Given the risk-off sentiment overnight, it is hard to expect to see a solid recovery in the Chinese yuan, after the currency touched lower due to somewhat improving virus headlines, according to the latest research report...

PBoC avows more rate cuts to offset coronavirus impact, says ANZ Research

The deputy governor of the Peoples Bank of China (PBoC), Chen Yulu, elaborated on recent monetary policy measures at a press conference held by the State Council on Monday, February 24. He outlined three measures to shore...

Surge in coronavirus cases fuels growth risks in South Korea, says Oxford Economics

The coronavirus outbreak is expected to dampen South Koreas exports and industrial production due to weaker Chinese demand. This is mainly due to the lockdowns in several Chinese cities and delays in economic activity...

Australian ANZ-Roy Morgan consumer confidence declines on weakness in financial conditions

Australias ANZ-Roy Morgan consumer confidence declined 0.7 percent last week, driven lower by weakness in financial conditions. Current finances fell 4 percent compared to the prior week, while future finances declined...

Politics

Donald Trump admin accused of withholding documents regarding foreign relations and policies

It was during the Senate Impeachment trials that it was made clear that members of the GOP, or more so, President Donald Trump and his administration, would try and withhold important information from the people who...

Donald Trump compiling names of officials included in 'hit list'

It is no secret that President Donald Trump appeared to be and still appears to be cleaning house shortly after getting acquitted from the Senate Impeachment trial. New reports have surfaced that shed more light on his...

Melania Trump reportedly lied under oath back in 2013

First Lady Melania Trumps citizenship has always been questioned by many even until now. Reports have resurfaced regarding the First Ladys past, revealing how she lied under oath back in 2013. As mentioned, reports have...

Melania Trump father Viktor Knavs reportedly has a criminal record

In filing for citizenship, especially in the United States, the person must have a squeaky clean record. However, it was recently revealed that First Lady Melania Trumps father Viktor Knavs, became a citizen despite having...

Science

SpaceX Starlink satellites to take part in US Air Force live-fire exercise

Because of the number of asteroids that have been coming close to the Earth, space agencies all over the world, and particularly in the United States like NASA, have begun developing defenses against otherworldly objects...

Archaeologists find secret chamber behind King Tutankhamun's tomb

King Tutankhamun is one of the most famous Egyptian royalties in history, with his golden tomb making him even more famous after his death. A discovery made by a group of archaeologists reveals that there is more to King...

Buzz Aldrin reveals he had his own moon landing strategy in mind during iconic moon landing mission

Neil Armstrong and Buzz Aldrin are known for being the first two people to ever set foot on the moon following the historic Apollo 11 mission. An old interview back in 2016 reveals that Aldrin had his own ideas as to how...

Asteroids: Study reveals that asteroid collisions can be beneficial for the environment

Asteroid collisions are mainly seen as a cause of concern and understandably so. However, a new study suggests that these space rocks can actually help the environment. Researchers from the University of Tsukuba studied...

Technology

‘League of Legends’ developer Riot Games says $10M is already a fair settlement for the gender discrimination lawsuit

Riot Games, the developer of the hit title League of Legends has released a statement to the ongoing lawsuit accusing the company of having a bro culture as well as gender discrimination. In its statement, the company...

‘Kingdom Hearts 3’ devs explain how the new ‘ReMind’ gameplay features work

The highly anticipated Kingdom Hearts 3: ReMind DLC is finally available to all players with access to the action role-playing game from Square Enix. Since the DLC has just launched on Xbox One, players using this platform...

‘The Sims 5’: 3 things to expect from its gameplay features

EA and Maxis are still all-out in pushing for new content and expansions packs for the current installment of their popular life simulation game. However, the rumor mill has been rife with expectations about the release...

Microsoft Surface Book 3 with 32GB of RAM could be announced this Spring

Microsoft will be launching the Surface Book 3 and the Surface Go 2 this coming Spring based on recent reports. There wont be major design changes to the exteriors of both devices, according to Petri. However, buyers can...

‘GTA 6’ news: Rockstar Games job listing spawns speculations that title might already be in its testing phase

At the moment, Rockstar Games has not confirmed that it is working on the GTA 6, the sequel to its highly successful Grand Theft Auto V title. But fans of the franchise are pretty convinced that its only a matter of time...
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