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Maciej F. Boni

Associate Professor of Biology, Pennsylvania State University
Epidemiology of influenza in the tropics. Tropical disease epidemiology. Treatment strategies and antimalarial drug resistance. mHealth and participatory epidemiology. Theory of infectious disease dynamics. Pathogen evolution, population genetics, phylogenetics, recombination.

From 2008 to 2016, I ran a research group in Ho Chi Minh City, Vietnam, focused on influenza epidemiology in the tropics and treatment strategies to delay or slow antimalarial drug resistance. My PhD students and other team members have been mathematical modelers, bioinformaticians, field site coordinators, and laboratory research assistants.

We have been running a large seroepidemiology study in southern Vietnam, aimed at reconstructing the disease dynamics of influenza virus including both symptomatic and asymptomatic influenza. This work has expanded to dengue virus, and we are also using the project to look at incidence of a number of other diseases, most recently Tetanus and Hepatitis B and E.

Since 2009, we have been running a community-based mHealth study on influenza-like illness (ILI) in Ho Chi Minh City. The study has collected over 40,000 data points and is currently used as a real-time epidemiology tool for Ho Chi Minh City. You can read about the study here .

Our malaria work is focused on designing and calibrating individual-based microsimulations. The microsimulations are used to compare different long-term drug distribution strategies to see which ones are most effective at delaying drug resistance. You can read about the most recent modeling results here and here. Our next goal is to perform health-economic analyses to determine if deploying multiple first-line therapies is an economically feasible strategy.

How big will the coronavirus epidemic be?

Mar 10, 2020 11:02 am UTC| Health

The Harvard historian Jill Lepore recounted recently in The New Yorker magazine that when democracies sink into crisis, the question where are we going? leaps to everyones mind, as if we were waiting for a weather forecast...

Economy

China Extends Gold Buying Streak as Reserves Surge Despite Volatile Prices

Chinas central bank has continued to strengthen its gold reserves, extending its buying streak to a 15th consecutive month in January, according to the latest data released by the Peoples Bank of China (PBOC). The move...

Trump Lifts 25% Tariff on Indian Goods in Strategic U.S.–India Trade and Energy Deal

President Donald Trump has signed a landmark executive order removing the 25% penalty tariff on Indian goods, signaling a major shift in U.S.India trade relations and global geopolitical alignment. The move functions as...

Trump Signs Executive Order Threatening 25% Tariffs on Countries Trading With Iran

U.S. President Donald Trump has signed a new executive order that could impose tariffs of up to 25% on countries that continue to do business with Iran, marking a significant escalation in Washingtons pressure campaign...

U.S.-India Trade Framework Signals Major Shift in Tariffs, Energy, and Supply Chains

The United States and India have taken a significant step toward a long-anticipated bilateral trade agreement by releasing an interim trade framework aimed at lowering tariffs, reshaping energy ties, and strengthening...

Dow Hits 50,000 as U.S. Stocks Stage Strong Rebound Amid AI Volatility

U.S. stocks surged on Friday, posting their strongest session since May 2025, as investors regained confidence following a turbulent week marked by sharp losses in technology shares and uncertainty around the artificial...

Politics

Ohio Man Indicted for Alleged Threat Against Vice President JD Vance, Faces Additional Federal Charges

A federal grand jury has returned an indictment against a 33-year-old Ohio man accused of threatening to kill U.S. Vice President JD Vance during the vice presidents visit to the Ohio region in January, according to the...

New York Legalizes Medical Aid in Dying for Terminally Ill Patients

New York has officially joined a growing number of U.S. states allowing medical aid in dying after Governor Kathy Hochul signed landmark legislation into law on Friday. The new New York medical aid in dying law permits...

Trump Says “Very Good Talks” Underway on Russia-Ukraine War as Peace Efforts Continue

U.S. President Donald Trump said on Friday that very good talks are ongoing regarding Russias war in Ukraine, signaling potential movement in long-running diplomatic efforts to end the conflict. Speaking briefly to...

China Warns US Arms Sales to Taiwan Could Disrupt Trump’s Planned Visit

China has issued a strong warning to the United States, signaling that any additional arms sales to Taiwan could seriously jeopardize U.S. President Donald Trumps planned visit to China in April. According to a report...

Trump Allows Commercial Fishing in Protected New England Waters

U.S. President Donald Trump has signed a proclamation permitting commercial fishing in a previously restricted marine protected area off the coast of New England, a move that has sparked renewed debate over ocean...

Science

SpaceX Prioritizes Moon Mission Before Mars as Starship Development Accelerates

Elon Musks SpaceX is shifting its near-term space exploration strategy, choosing to prioritize a return to the Moon before pursuing missions to Mars, according to a recent Wall Street Journal report citing sources familiar...

NASA and SpaceX Target Crew-11 Undocking From ISS Amid Medical Concern

NASA has confirmed that the agency, in coordination with SpaceX, is targeting no earlier than 5 p.m. Eastern Time (2200 GMT) on Wednesday, January 14, for the undocking of the SpaceX Crew-11 mission from the International...

Neuralink Plans High-Volume Brain Implant Production and Fully Automated Surgery by 2026

Elon Musks brain-computer interface company Neuralink is preparing for a major expansion, announcing plans to begin high-volume production of its brain implant devices and transition to a fully automated surgical procedure...

Jared Isaacman Confirmed as NASA Administrator, Becomes 15th Leader of U.S. Space Agency

The U.S. Senate has officially confirmed billionaire private astronaut Jared Isaacman as the new NASA administrator, making him the 15th leader in the agencys history. The confirmation, which took place on Wednesday, marks...

Senate Sets December 8 Vote on Trump’s NASA Nominee Jared Isaacman

The U.S. Senate Commerce Committee announced it will vote on December 8 on President Donald Trumps renewed nomination of private astronaut and tech entrepreneur Jared Isaacman to lead NASA. Isaacman, known for his...

Technology

Nvidia CEO Jensen Huang Says AI Investment Boom Is Just Beginning as NVDA Shares Surge

Nvidia (NASDAQ: NVDA) CEO Jensen Huang reaffirmed his bullish stance on artificial intelligence, calling the massive capital expenditure flowing into AI infrastructure both appropriate and necessary as the industry...

Amazon Stock Rebounds After Earnings as $200B Capex Plan Sparks AI Spending Debate

Amazon.com (NASDAQ:AMZN) delivered a mixed but closely watched earnings report, beating Wall Street expectations on revenue while unveiling a massive long-term investment plan that unsettled investors. The e-commerce and...

Global PC Makers Eye Chinese Memory Chip Suppliers Amid Ongoing Supply Crunch

Major PC manufacturers including HP, Dell, Acer, and Asus are reportedly exploring the option of sourcing memory chips from Chinese semiconductor companies for the first time, as a prolonged global supply crunch continues...

OpenAI Expands Enterprise AI Strategy With Major Hiring Push Ahead of New Business Offering

OpenAI is significantly accelerating its enterprise AI strategy by hiring hundreds of new employees for its technical consulting division, according to a report by The Information, citing a person familiar with the...

SoftBank Shares Slide After Arm Earnings Miss Fuels Tech Stock Sell-Off

SoftBank Group Corp. (TYO:9984) shares tumbled sharply on Thursday, tracking a steep decline in Arm Holdings (NASDAQ:ARM) after the UK-based chip designer reported weaker-than-expected earnings for the December quarter....