SYDNEY, Australia, Oct. 31, 2017 -- Prima BioMed Ltd (ASX:PRR) (NASDAQ:PBMD) (“Prima”) announces that Dr. Frédéric Triebel, Prima’s Chief Scientific Officer and Medical Officer, gave an oral presentation at the World Immunotherapy Congress 2017 in Basel, Switzerland at 5.50pm CEST on October 31, 2017.
The presentation included the following information and data:
- Overview of Lymphocyte Activation Gene-3 (LAG-3) and its structural relationship to the other MHC class II ligand, CD4;
- Therapeutic potential of engaging (in cancer) or suppressing (in auto-immune diseases) the human immune response by modulating either LAG-3 or its ligand MHC class II;
- Overview of the unique structure of Prima’s lead product candidate, eftilagimod alpha (LAG-3Ig or IMP321), as a MHC class II agonist and antigen presenting cell activator; and
- Review of Prima’s ongoing oncology-focused clinical trials of eftilagimod alpha (AIPAC, TACTI-mel and INSIGHT) including:
- Immune monitoring data from the run-in phase of the AIPAC clinical trial showing robust infiltration of T cells around tumor noduleswith some T cells infiltrating the nodules following 13 eftilagimod alpha s.c. injections in a metastatic breast cancer patient treated with paclitaxel weekly; and
- Three patients have been recruited for Stratum A (intratumoral (i.t.)) and Stratum B (intraperitoneal (i.p.)) of the INSIGHT clinical trial.
The TACTI-mel Phase 1 clinical trial, being undertaken in Australia, is investigating the use of eftilagimod alpha in combination with pembrolizumab (KEYTRUDA) in metastatic melanoma patients. The patients eligible to participate in the TACTI-mel Phase 1 clinical trial are those that have either had no response or a suboptimal response to KEYTRUDA monotherapy as a first-line of treatment.
New data in relation to the first and second patient cohort of TACTI-mel will be presented at the Society for Immunotherapy of Cancer (SITC) 2017 meeting on 10-12 November, as previously announced.
A copy of Dr Triebel’s presentation slides presented at the World Immunotherapy Congress 2017 is available on Prima’s website in the Presentations section of the Investors tab at http://primabiomed.com.au/investor/presentations.php
Prima BioMed
Prima BioMed is listed on the Australian Securities Exchange and on the NASDAQ in the US. For further information please visit www.primabiomed.com.au.
For further information please contact:
U.S. Investors:
Jay Campbell, Vice President of Business Development and Investor Relations, Prima Biomed
+1 (917) 860-9404; [email protected]
Matthew Beck, The Trout Group LLC
+1 (646) 378-2933; [email protected]
Australian Investors/Media:
Matthew Gregorowski, Citadel-MAGNUS
+61 2 8234 0105; [email protected]


Amazon Stock Rebounds After Earnings as $200B Capex Plan Sparks AI Spending Debate
Baidu Approves $5 Billion Share Buyback and Plans First-Ever Dividend in 2026
Once Upon a Farm Raises Nearly $198 Million in IPO, Valued at Over $724 Million
Nvidia, ByteDance, and the U.S.-China AI Chip Standoff Over H200 Exports
Trump Backs Nexstar–Tegna Merger Amid Shifting U.S. Media Landscape
Sony Q3 Profit Jumps on Gaming and Image Sensors, Full-Year Outlook Raised
TSMC Eyes 3nm Chip Production in Japan with $17 Billion Kumamoto Investment
TrumpRx Website Launches to Offer Discounted Prescription Drugs for Cash-Paying Americans
Rio Tinto Shares Hit Record High After Ending Glencore Merger Talks
Hims & Hers Halts Compounded Semaglutide Pill After FDA Warning
Ford and Geely Explore Strategic Manufacturing Partnership in Europe
Washington Post Publisher Will Lewis Steps Down After Layoffs
Global PC Makers Eye Chinese Memory Chip Suppliers Amid Ongoing Supply Crunch
Weight-Loss Drug Ads Take Over the Super Bowl as Pharma Embraces Direct-to-Consumer Marketing
CK Hutchison Launches Arbitration After Panama Court Revokes Canal Port Licences
Toyota’s Surprise CEO Change Signals Strategic Shift Amid Global Auto Turmoil
SpaceX Pushes for Early Stock Index Inclusion Ahead of Potential Record-Breaking IPO 



