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Yifeng Cheng

Ph.D. Candidate, Texas A&M University Health Science Center, Texas A&M University

My research interest is to study neural circuit mechanisms of addictive behavior. As a Ph.D. candidate in the laboratory of Dr. Jun Wang, I investigate the role of dopamine D1 and D2 receptor-expressing (D1R and D2R) medium spiny neurons (MSNs) within the corticostriatal circuit in alcohol addiction. My research is focused on afferent input-specific and cell type-specific mechanisms underlying excessive alcohol consumption in a mouse model of alcohol addiction. To perform the research, I have been trained to use and am currently able to utilize board techniques, including state-of-the-art optogenetics and chemicogentics (Designer Receptors Exclusively Activated by Designer Drug, DREADDs), to in vivo manipulate the activity of specific populations of neurons in the corticostriatal circuit of Bacterial Artificial Chromosome (BAC) transgenic mice. With this research, I hope to understand of how a specific neuronal population is involved in addiction-related behaviors, such as pathological excessive alcohol intake. My ultimate career goal is to find new therapeutic approaches to treat alcohol addiction.

Alcoholism research: A virus could manipulate neurons to reduce the desire to drink

Oct 25, 2016 18:34 pm UTC| Health

About 17 million adults and more than 850,000 adolescents had some problems with alcohol in the United States in 2012. Long-term alcohol misuse could harm your liver, stomach, cardiovascular system and bones, as well as...

Economy

Beyond the spin, beyond the handouts, here’s how to get a handle on what’s really happening on budget night

Three weeks from now, some of us will be presented with a mountain of budget papers, and just about all of us will get to hear about them on radio, TV or news websites on budget night. The quickest way to find out what...

Johannesburg in a time of darkness: Ivan Vladislavić’s new memoir reminds us of the city’s fragility

Ivan Vladislavić is Johannesburgs literary linkman. He tells us, in the first pages of his new book, The Near North, that before cities were lit, first by gaslight and later electricity, people of means paid torchbearers...

Economist Chris Richardson on an ‘ugly’ inflation result and the coming budget

With Jim Chalmerss third budget on May 14, Australians will be looking for some more cost-of-living relief beyond the tax cuts although they have been warned extra measures will be modest. As this weeks consumer price...

Inflation is slowly falling, while student debt is climbing: 6 graphs that explain today’s CPI

Australias inflation rate has fallen for the fifth successive quarter, and its now less than half of what it was back in late 2022. The annual rate peaked at 7.8% in the December quarter of 2022 and is now just 3.6%, in...

Extraordinary Vietnam fraud case exposes the inherent vulnerabilities of banks

The financial crisis of 2008 showed just how much the world depends on banks being well run. Since then, regulators have been given new powers to keep some of the biggest institutions on a much shorter leash to stamp out...

Politics

US Urges China, Russia to Reject AI Control in Nuclear Arms, Align with Global Norms

Paul Dean, a senior U.S. arms control official, emphasized the critical need for China and Russia to join the U.S. in declaring that humans will always decide on the deployment of nuclear weapons, not artificial...

Labour can afford to be far more ambitious with its economic policies – voters are on board

To say that the Labour party is flying high in the polls is something of an understatement. But despite its consistent lead against the Tories, the opposition finds itself in a rather odd position: on the cusp of power but...

History for sale: what does South Africa’s struggle heritage mean after 30 years of democracy?

One of my favourite statues is the one of Nelson Mandela at the Sandton City shopping centre in Johannesburg. Larger than life, its oversized bronze shoes shimmer in the evening light, polished by the hands of many...

Sudan: civil war stretches into a second year with no end in sight

In the early hours of April 15 2023, the Rapid Support Forces (RSF) a Sudanese paramilitary force attacked the military airstrip in the town of Merowe and deployed troops across strategic locations in Sudans capital,...

Military conscription is returning to Europe, but is it really a more equal way of mobilising? What history tells us

The idea that conscription, defined as the compulsory enlistment of citizens for military service, can increase equality and instil a sense of solidarity that transcends traditional societal divides has echoed throughout...

Science

A Nasa rover has reached a promising place to search for fossilised life on Mars

While we go about our daily lives on Earth, a nuclear-powered robot the size of a small car is trundling around Mars looking for fossils. Unlike its predecessor Curiosity, Nasas Perseverance rover is explicitly intended to...

The rising flood of space junk is a risk to us on Earth – and governments are on the hook

A piece of space junk recently crashed through the roof and floor of a mans home in Florida. Nasa later confirmed that the object had come from unwanted hardware released from the international space station. The 700g,...

Peter Higgs was one of the greats of particle physics. He transformed what we know about the building blocks of the universe

Peter Higgs, who gave his name to the subatomic particle known as the Higgs boson, has died aged 94. He was always a modest man, especially when considering that he was one of the greats of particle physics the area of...

Could a telescope ever see the beginning of time? An astronomer explains

The James Webb Space Telescope, or JWST for short, is one of the most advanced telescopes ever built. Planning for JWST began over 25 years ago, and construction efforts spanned over a decade. It was launched into space on...

US media coverage of new science less likely to mention researchers with African and East Asian names

When one Chinese national recently petitioned the U.S. Citizenship and Immigration Services to become a permanent resident, he thought his chances were pretty good. As an accomplished biologist, he figured that news...

Technology

2025 Sees SK hynix's HBM Chips Fully Booked Amidst AI Surge

SK hynix, a key player in the artificial intelligence (AI) services sector, made a significant announcement on Thursday. HBM Sales Reflect SK hynixs Market Leadership Its high-bandwidth memory (HBM) processors,...

Bitcoin Price May Consolidate for Two Months Post-Halving, Says Bitfinex

As the cryptocurrency market adjusts to the latest Bitcoin halving, analysts from Bitfinex forecast a price consolidation period of up to two months, with significant price fluctuations expected within this...

Former PayPal President Predicts Bitcoin as AI's Future Currency

Amid fluctuating prices, former PayPal President David Marcus champions Bitcoin as the native currency of AI at the Bitcoin for Corporations 2024 event, rekindling interest and optimism in the cryptocurrencys long-term...

Massive Shiba Inu Transfer: 1.75 Trillion SHIB Moves, Sparks Market Excitement

On May 2, Whale Alert tracked two enormous transfers totaling 1.75 trillion Shiba Inu (SHIB) tokens from Robinhood, driving a more than 6% increase in SHIBs price and igniting bullish sentiment among...

Anthropic Launches Claude AI App on iPhone to Rival OpenAI’s ChatGPT

Anthropic PBC, an artificial intelligence startup established in 2021, announced on Wednesday, May 1, that it launched an iOS app for its Claude 3 AI chatbot or language models. The company also unveiled a new subscription...