Cesca Therapeutics Announces Evaluation Agreement With The University Of North Carolina Lineberger Advanced Cellular Therapeutics Facility for X-Series™ Products That Provide Automated, Closed System Cellular Processing

RANCHO CORDOVA, Calif., April 24, 2018 -- Cesca Therapeutics Inc. (NASDAQ:KOOL), a market leader in automated cell processing and point-of-care, autologous cell-based therapies, today announced that it has entered into an evaluation agreement with the University of North Carolina Lineberger Advanced Cellular Therapeutics Facility (ACT) to assess Cesca’s patented and proprietary X-Series products for automated, closed system cellular processing.

X-Series products are part of Cesca’s CAR-TXpress™ platform, which is an automated system that selects target cells using its patented, buoyancy-activated cell separation (X-BACS™) technology. The system is a multi-device platform designed to automate many of the manual steps currently involved in cell processing. As such, the CAR-TXpress system can provide a comprehensive and commercially viable, automated cellular manufacturing and control (CMC) solution for the development of CAR-T as well as CAR-NK therapeutics.

“As a pioneer in the research and development of novel CAR-T based therapeutics, we are delighted that ACT has selected our X-Series products for this important evaluation,” said Phil Coelho, chief technology officer of ThermoGenesis, Cesca’s device subsidiary. “The complexity of the CAR-T manufacturing process stands as a significant obstacle to the more rapid uptake of these ground-breaking therapies, contributing to lengthy treatment times and high costs. We believe CAR-TXpress can automate key steps in the process while at the same time improving cell yields and consistency. We are hopeful that this evaluation will lead to a long and productive collaboration with ACT.”    

Under the terms of the agreement, Cesca will be responsible for providing its X-Series products, along with required training and support. Cesca will receive from ACT data regarding improvements in speed, yield, efficiency and consistency as compared to ACT’s existing legacy CAR-T cell manufacturing process.    

About Cesca Therapeutics Inc. 
Cesca Therapeutics develops, commercializes and markets a range of automated technologies for CAR-T and other cell-based therapies. Its device division, ThermoGenesis, provides a full suite of solutions for automated clinical biobanking, point-of-care applications, and automation for immuno-oncology. The Company is developing an automated, functionally-closed CAR-TXpress™ platform that addresses the critical unmet need for better cellular manufacturing and controls (CMC) for the emerging CAR-T immunotherapy market. Cesca is an affiliated company of China-based Boyalife Group.

Forward-Looking Statement 
The statements contained herein may include statements of future expectations and other forward-looking statements that are based on management’s current views and assumptions and involve known and unknown risks and uncertainties that could cause actual results, performance or events to differ materially from those expressed or implied in such statements. A more complete description of risks that could cause actual events to differ from the outcomes predicted by Cesca Therapeutics’ forward-looking statements is set forth under the caption "Risk Factors" in Cesca Therapeutics’ annual report on Form 10-K and other reports it files with the Securities and Exchange Commission from time to time, and you should consider each of those factors when evaluating the forward-looking statements.

Company Contact:
Cesca Therapeutics Inc.
Wendy Samford
916-858-5191
[email protected] 

Investor Contact:
Rx Communications
Paula Schwartz
917-322-2216
[email protected]