FCC Approves Expansion of SpaceX Starlink Network With 7,500 New Satellites 
China’s AI Sector Pushes to Close U.S. Tech Gap Amid Chipmaking Challenges 
Stellantis to End Plug-In Hybrid Sales in the U.S. as Demand Shifts Toward Traditional Hybrids 
Chevron Sees Path to Boost Venezuela Oil Output by 50% After Trump Administration Talks 
Boeing 737 MAX 10 Advances in FAA Testing as Certification Delays Continue 
Anthropic Launches HIPAA-Compliant Healthcare Tools for Claude AI Amid Growing Competition 
Nvidia Appoints Former Google Executive Alison Wagonfeld as First Chief Marketing Officer 
GM Takes $6 Billion EV Write-Down as Electric Vehicle Demand Slows in the U.S. 
Trump Considers Starlink to Restore Internet Access in Iran Amid Protests 
Hanwha Ocean Shares Rise on Plans to Expand U.S. Shipbuilding Capacity 
Supreme Court to Hear Cisco Appeal on Alien Tort Statute and Human Rights Liability 
Trump Pushes $100 Billion U.S. Oil Investment Plan for Venezuela After Maduro Seizure 
UBS Upgrades L’Oréal to Buy, Sees Strong Sales Momentum and 20% Upside 
Walmart to Join Nasdaq-100 Index as It Replaces AstraZeneca Following Exchange Move 
Johnson & Johnson Secures Tariff Exemption by Agreeing to Lower Drug Prices in the U.S. 
BURLINGAME, Calif., March 20, 2017 -- Corvus Pharmaceuticals, Inc. (Nasdaq:CRVS), a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immuno-oncology therapies, today announced that it will present interim data from its ongoing Phase 1/1b study of CPI-444 as a single agent and in combination with Genentech’s Tecentriq® (atezolizumab) in an oral plenary session at the American Association for Cancer Research (AACR) Annual Meeting 2017, which is taking place April 1-5 in Washington, D.C. The Company will also present preclinical and clinical data on CPI-444, as well as preclinical data on its investigational humanized monoclonal anti-CD73 antibody, in poster presentations. In a separate invited oral presentation, CPI-444 will be featured as a novel oral checkpoint inhibitor of adenosine mediated suppression of tumor immunity. The following are details for the six oral and poster presentations. The abstract for the oral plenary session will be available on the AACR website on March 31 at 4:30 p.m. ET.
Oral Presentations
Abstract #: CT119
Title: CPI-444, an oral adenosine A2a receptor (A2AR) antagonist, demonstrates clinical activity in patients with advanced solid tumors
Presenter: Leisha Emens, M.D., Ph.D., associate professor of oncology, John Hopkins Sidney Kimmel Comprehensive Cancer Center
Session Type: Oral Plenary
Presentation Date and Time: Tuesday, April 4, 10:30 a.m.-12:45 p.m. ET
Location: Ballroom C, Level 3, Washington Convention Center
Title: CPI-444 – A Novel Oral Checkpoint Inhibitor of Adenosine Mediated Suppression of Tumor Immunity
Presenter: Ian McCaffery, Ph.D., Corvus Pharmaceuticals
Session Type: Invited Oral
Presentation Date and Time: Saturday, April 1, 3:15-5:15 p.m. ET
Location: Ballroom A-B, Level 3, Washington Convention Center
Poster Presentations
Abstract #: 5593/Poster #: 25
Title: Inhibition of A2AR induces anti-tumor immunity alone and in combination with anti-PD-L1 in preclinical and clinical studies
Presenter: Stephen Willingham, Ph.D., Corvus Pharmaceuticals
Presentation Date and Time: Wednesday, April 5, 8:00 a.m-12:00 p.m. ET
Location: Convention Center, Halls A-C, Poster Section 24
Abstract #: 5598/Poster #: 30
Title: Adenosine signaling through A2AR limits the efficacy of anti-CTLA4 and chemotherapy in preclinical models
Presenter: Po Y. Ho, Corvus Pharmaceuticals
Presentation Date and Time: Wednesday, April 5, 8:00 a.m-12:00 p.m. ET
Location: Convention Center, Halls A-C, Poster Section 24
Abstract #: 5579/Poster #: 11
Title: Strategic inhibition of adenosine A2A receptor (A2AR) by CPI-444 improves CD8+:Treg ratios and enhances T-cell killing of a HER-2/neu expressing murine tumor
Presenter: Blake A. Scott, Johns Hopkins University School of Medicine
Presentation Date and Time: Wednesday, April 5, 8:00 a.m-12:00 p.m. ET
Location: Convention Center, Halls A-C, Poster Section 24
Abstract #: 5577/Poster #: 9
Title: A novel CD73-blocking antibody reduces production of immunosuppressive adenosine and restores T-cell function
Presenting Author: Emily Piccione, Ph.D., Corvus Pharmaceuticals
Presentation Date and Time: Wednesday, April 5, 8:00 a.m.-12:00 p.m. ET
Location: Convention Center, Halls A-C, Poster Section 24
About Corvus Pharmaceuticals
Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company focused on the development and commercialization of small molecule and antibody agents that target the immune system to treat patients with cancer. These agents block or modify crucial immune checkpoints and reprogram immune T-cells. Corvus’ lead product, CPI-444, is a checkpoint inhibitor that is designed to disable a tumor’s ability to subvert attack by the immune system by inhibiting adenosine in the tumor microenvironment. CPI-444 is a small molecule that is taken orally. CPI-444 is currently being evaluated in a multicenter Phase 1/1b clinical trial in patients with various solid tumors. This successive expansion cohort trial is examining the activity of CPI-444 both as a single agent and in combination with Genentech’s Tecentriq (atezolizumab), an anti-PD-L1 antibody. Corvus is conducting the trial with Genentech, a member of the Roche Group, under a clinical trial collaboration the two companies entered into in October 2015. For more information, visit www.corvuspharma.com.
Tecentriq® is a registered trademark of Genentech.
Corvus Contact: Jason Coloma SVP, Chief Business Officer Corvus Pharmaceuticals, Inc. +1-650-900-4511 [email protected] Media Contact: Julie Normart Pure Communications +1-415-946-1087 [email protected]
